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Phosphatidylinositol deacylase

From Wikipedia, the free encyclopedia
phosphatidylinositol deacylase
Identifiers
EC no.3.1.1.52
CAS no.81604-94-6
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
Search
PMCarticles
PubMedarticles
NCBIproteins

The enzyme phosphatidylinositol deacylase (EC 3.1.1.52) catalyzes the reaction

1-phosphatidyl-D-myo-inositol + H2O 1-acylglycerophosphoinositol + a carboxylate

This enzyme belongs to the family of hydrolases, specifically those acting on carboxylic ester bonds. The systematic name is 1-phosphatidyl-D-myo-inositol 2-acylhydrolase. Other names in common use include phosphatidylinositol phospholipase A2, and phospholipase A2.

References

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  • Gray NC, Strickland KP (1982). "The purification and characterization of a phospholipase A2 activity from the 106,000 X g pellet (microsomal fraction) of bovine brain acting on phosphatidylinositol". Can. J. Biochem. 60 (2): 108–17. doi:10.1139/o82-015. PMID 7083039.
  • Gray NC, Strickland KP (1982). "On the specificity of a phospholipase A2 purified from the 106,000 X g pellet of bovine brain". Lipids. 17 (2): 91–6. doi:10.1007/BF02535181. PMID 7087686.